Last edited by Vitilar
Monday, July 13, 2020 | History

7 edition of Paf in Asthma (Perspectives in Asthma Series, Vol 3) found in the catalog.

Paf in Asthma (Perspectives in Asthma Series, Vol 3)

G. Holme

Paf in Asthma (Perspectives in Asthma Series, Vol 3)

by G. Holme

  • 138 Want to read
  • 25 Currently reading

Published by Academic Press .
Written in English

    Subjects:
  • Pharmacology,
  • Respiratory medicine,
  • Pulmonary & Thoracic Medicine,
  • Asthma,
  • Pharmacology (Specific Aspects),
  • Medical / Nursing,
  • Health/Fitness

  • Edition Notes

    ContributionsJ. Morley (Editor)
    The Physical Object
    FormatHardcover
    Number of Pages328
    ID Numbers
    Open LibraryOL10071722M
    ISBN 100123533406
    ISBN 109780123533401

    The inflammatory response is the key mechanism responsible for asthma, and the pro-inflammatory platelet-activating factor (PAF) is known to play a role in the pathology of bronchial asthma. In this study, we stimulated human bronchial smooth muscle cells (HBSMCs) with PAF and examined the effects of HSYA on the resulting asthma-related : Xinjing Guo, Meng Zheng, Ruiyan Pan, Baoxia Zang, Jianwei Gao, Hanying Ma, Ming Jin. Now available in its Third Edition, Asthma: Basic Mechanisms and Clinical Management has become the reference text in asthma. This highly successful text sheds new light on the basic physiological and molecular mechanisms of asthma, how current treatments work, and how best to apply the latest knowledge to control this important disease. The Third Edition has .

      Development of Anti-Asthma Drugs reviews existing asthma treatments and novel approaches currently under investigation, in the context of their mode of action and clinical effectiveness, in the hope that this might lead to a greater understanding of the factors involved in the expression of the disease and, therefore, in the design of better Edition: 1. Platelets are a kind of blood cells derived from bone marrow megakaryocytes and play essential roles in thrombosis, hemostasis, and tissue repair. Platelets have been found to be crucially involved in various immune responses and actively involved in the pathogenesis of allergic diseases such as allergic asthma. Patients with allergic asthma have lower platelet counts Author: Mirjana Turkalj, Ivana Banic.

    Most of the books are available both as hardcover books and as paperbacks, and some are also available as e-books. Questions & Answers About Asthma In this authoritative guide book, Dr. Claudia S. Plottel provides practical answers to asthmatic people and their families about the development of this chronic disease, treatment options. Asthma cannot be diagnosed without a breathing test. So, if you think you may have asthma, tell your health care provider (HCP) about all of your symptoms. If your HCP thinks your symptoms may be from asthma, they will ask you to have a breathing test called a pulmonary function test or spirometry test (See Patient Education Series.


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Paf in Asthma (Perspectives in Asthma Series, Vol 3) by G. Holme Download PDF EPUB FB2

Paf in Asthma (Perspectives in Asthma Series) by G. Holme (Author), J. Morley (Editor) ISBN PAF is now recognized as a molecule having a diverse range of biological effects relevant to allergic inflammation and asthma including the abili ty to induce long lasting airway inflammation and associated increases in bronchial : Paperback.

PAF is now recognized as a molecule having a diverse range of biological effects relevant to allergic inflammation and asthma including the abili ty to induce long lasting airway inflammation and associated increases in bronchial : Birkhäuser Basel. Examines the chemistry, biochemistry, and biology of platelet activating factor (PAF) and considers the effect of existing anti-asthma drugs on responses to PAF to gain knowledge on the prospects for Read more.

COVID Resources. Reliable information about the coronavirus (COVID) is available from the World Health Organization (current situation, international travel).Numerous and frequently-updated resource results are available from this ’s WebJunction has pulled together information and resources to assist library staff as they consider how to handle.

Platelet-activating factor (PAF) is a lipid mediator involved in several allergic reactions. It is released from multiple cells of the immune system, such as eosinophils, neutrophils, and mast cells, and also exerts its effect on most of them upon specific binding to its receptor, becoming a pleiotropic mediator.

PAF is considered a potential relevant mediator in allergic rhinitis, with a Cited by: 1. This chapter discusses several asthma mediators, such as histamine (H), platelet-activating factor (PAF), and oxygen radicals. H is a potent inducer of bronchoconstriction and causes airway microvascular leakage in the bronchial microvasculature—effects that are mediated through H 1 receptors.

It also induces the secretion of mucous glycoproteins from human. Abstract: PAF is a potent proinflammatory mediator which plays a role in different inflammatory diseases, including bronchial asthma.

PAF is able to induce key pathogenic features of asthma and to influence the activity of cells involved in immune-inflammatory process; it may therefore serve as a possible direct target for anti-asthmatic drugs. This study was designed to examine further the role of platelet-activating factor (PAF) in asthma, comparing leukotriene B4 (LTB4) release, 5-lipoxygenase activity and intracellular calcium levels ([Ca2+]i) in macrophages.

LTB4 and other lipoxygenase metabolites in macrophages in bronchoalveolar lavage fluids obtained from 23 asthmatic patients and 20 Cited by: Patient Advocate Foundation (PAF) programs and services are fully operational. As the coronavirus spreads across the country, PAF wants to make sure you have answers and resources to support you during this uncertain and stressful time.

Platelet activating factor (PAF) is a potent phospholipid mediator involved in anaphylaxis and chronic inflammatory disorders, including bronchial asthma. PAF is able to act both, directly as a chemotactic factor and indirectly through the release of other inflammatory agents.

Apart from its known potent ability to activate platelets, PAF influences other immune Cited by: To investigate the role of platelet activating factor (PAF) in the immediate asthmatic response, we examined the bronchial reactivity to histamine after administration of PAF to guinea-pigs or antigen challenge to passively sensitized guinea-pigs.

A bolus injection of PAF ( ng kg-1), which did not cause a significant increase in Cited by:   Platelet-activating factor (PAF) is a lipid mediator involved in several allergic reactions. It is released from multiple cells of the immune system, such as eosinophils, neutrophils, and mast cells, and also exerts its effect on most of them upon specific binding to its receptor, becoming a pleiotropic by: 1.

Asthma books are a great way to learn about asthma management and free is even better. Learn everything that you need to know to stay symptom-free.

Download any of the asthma books listed below. Learn how to control your asthma symptoms anytime and anywhere. Title: Platelet-Activating Factor (PAF): A Review of its Role in Asthma and Clinical Efficacy of PAF Antagonists in the Disease Therapy VOLUME: 2 ISSUE: 1 Author(s):Alicja Kasperska-Zajac, Zenon Brzoza and Barbara Rogala Affiliation:Chair and Clinical Department of Internal Diseases, Allergology and Clinical Immunology, ul.

3-go MajaZabrzeby: Platelet-activating factor, also known as PAF, PAF-acether or AGEPC, is a potent phospholipid activator and mediator of many leukocyte functions, platelet aggregation and degranulation, inflammation, and anaphylaxis.

It is also involved in changes to vascular permeability, the oxidative burst, chemotaxis of leukocytes, as well as augmentation of arachidonic acid metabolism in phagocytes.

PAF CAS Number: Platelet-activating factor (PAF) is a potent inflammatory mediator that mimics many of the features of asthma, including eosinophil recruitment and activation and induction of AHR; yet even potent PAF antagonists, such as dominant, do not control asthma symptoms, at least in chronic asthma.

PAF was calculated for: idiopathic pulmonary fibrosis (26%), asthma (16%), COPD (14%), chronic bronchitis (13%) and community-acquired pneumonia in working-age adults (10%).

Occupational burden estimates were calculated for sarcoidosis (30%), pulmonary alveolar proteinosis (29%), hypersensitivity pneumonitis (19%) and tuberculosis in silica. Book The child in this story suffers from asthma, a chronic condition that sometimes produces frightening attacks.

But kids learn that with proper medical supervision and treatment, asthma can be kept under control, and kids who are affected by it can live happy, active, and normal lives/5. asthma (ăz´mə, ăs´–), chronic inflammatory respiratory disease characterized by periodic attacks of wheezing, shortness of breath, and a tight feeling in the chest.A cough producing sticky mucus is symptomatic.

The symptoms often appear to be caused by the body's reaction to a trigger such as an allergen (commonly pollen, house dust, animal dander: see. A comprehensive review of all aspects of modern asthma care, including diagnosis, epidemiology, pathophysiology, and appropriate investigations.

This chapter covers both acute and chronic disease, including the specific areas of refractory asthma, occupational asthma, and asthma in pregnancy. The emergency management of acute severe asthma is covered. PSAP BOOK 2 • Pulmonary and mergency edicine 10 Asthma and COPD Table Comparison of Features of Asthma, COPD, and ACOS (continued) Clinical Feature Asthma COPD Suggestive of ACOS History Family history of atopy (e.g., asthma, allergic rhinitis, eczema) Exposure to tobacco in utero 20+ pack-year personal history of tobacco useFile Size: KB.An asthma attack can occur when you are exposed to things in the environment such as house dust mites and tobacco smoke.

These are called asthma triggers. Some of the most important triggers are listed to the right with additional guidelines in the section titled “Important Asthma Triggers.” 4. 9/5/06 AM Page